(a) Sickle cell anaemia – When because of point mutation there is substitution of glutamic acid by valine in the sixth position of the beta globulin chain of haemoglobin, the biconcave shape of haemoglobin converts into sickle shape. This leads to decreased oxygen transport in blood, weakness
(b) Phenylketonuria – Person affected from phenylketonuria lacks an enzyme which converts amino acid and phenylalanine into tyrosine. Then this phenylalanine accumulates and converts into phenyl pyruvic acid and other derivatives. This disease causes mental retardation. Due to their poor absorption in kidney they are excreted in the urine.Answered by Abhisek | 1 year ago
Who had proposed the chromosomal theory of inheritance?
What is point mutation? Give one example.
Explain the terms with example Incomplete dominance
Explain the terms with example Co-dominance
A child has blood group O. If the father has blood group A and mother blood group B, work out the genotypes of the parents and the possible genotypes of the other offspring.